PROTEOLYTIC ENZYME SYSTEMS IN DEVELOPING RAT TISSUES
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چکیده
منابع مشابه
Changes in proteolytic enzyme systems of rat tissues in response to heterologous growth of human ovarian tumors.
Studies were made to determine the effect of heterologous growth of a human ovarian tumor on the proteolytic enzyme system of various tissues of weanling rats conditioned with cortisone and x-radiation. Conditioning per se had no effect on the activities of the tissues studied. Significant increases were observed in both aminopeptidase and cathepsin B activities of liver, kidney, and spleen of ...
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Various serine proteases (e.g., trypsin, alpha-chymotrypsin, Pronase, and subtilisin) stimulate adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity in a membrane-enriched fraction of the rat ovary. Maximum stimulation is observed at protease concentrations ranging from 3 to 10 mug/ml. Higher protease concentrations inhibit ovarian adenylate cyclase in a dose-dependent m...
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A sensitive assay system, optimally supplemented with tritiated protocollagen substrate and cofactors, is described which is suitable for determining the peptidyl proline hydroxylase (PPH) content of a wide spectrum of rat tissues. In most tissues, less than 50 percent of the total activity was soluble; the particulate portion of the activity (concentrated in the mitochondrial and microsomal fr...
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The angiotensin I-converting enzyme (ACE) converts the inactive angiotensin I molecule to the active angiotensin II. ACE is rich in epithelium, endothelium, and neuroepithelial cells and it found largely on the brush border of intestine and kidney proximal tubules. ACE also presents in the serum. Some pulmonary and renal toxic drugs change the serum and tissue ACE contents. In this research ACE...
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1. A proteolytic enzyme with some features of a carboxypeptidase has been purified some 1180-fold from the sap of French beans (Phaseolus vulgaris var. Prince). A bright blue protein, plastocyanin, was separated from the enzyme by DEAE-cellulose chromatography. 2. Unlike carboxypeptidase A or B of animal origin, there is no evidence that the enzyme is a metalloprotein. There was no stimulation ...
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ژورنال
عنوان ژورنال: Reproduction
سال: 1968
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0170019